ÇOCUKLARDA HELİKOBAKTER PYLORİ ENFEKSİYONU İLE PLAZMA 25 HİDROKSİ VİTAMİN D3 DÜZEYİ ARASINDAKİ İLİŞKİ

OBJECTIVE: The severity of the Helicobacter pylori (H.pylori) infection and presence H.pylori related diseases are affected by host, bacterial environmental factors. In this study it is aimed to show relationship between plasma Vitamin D3 (vitD3) has significant role in regulation inflamatory response children with infection. MATERIAL AND METHODS: Two hundred one patients aged 3-18 years, referred pediatric gastroentrology department Celal Bayar University Medical Faculty March 2010 2011 performed upper gastrointestinal endoscopy because symptoms iron deficiency anemia refractory medical therapy were enrolled study. Histopathologic diagnosis biopsy speciments evaluated. There 98 positive group 103 negative group. Plasma level vitD3 cases compared. Relationship gastric mucosal activity degree inflammation evaluated RESULTS: levels low 80 (81.6%) 76 (73%) patients. This difference was not statistically (p>0.05). mean value groups 15.64±8.9 ng/mL 16.36±11.35 respectively. When classified according four different as severe deficiency, insuficiency sufficiency. more frequent than (p<0.05). Severity chronic inflamation tissue increased inversely both CONCLUSIONS: Results suggests that common our region. risk factor for findings shows increasing antibacterial effect reducing